Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. Diffuse axonal injury (DAI), or lesions on the brain’s connective nerve fibers, is a common condition resulting from TBI. Previous research has found that the location and characteristics of diffuse axonal injury may contribute to different outcomes, including level of function and survival....

Pediatric traumatic brain injury (TBI) is a public health concern, accounting for an estimated 600,000 emergency room visits each year in the United States. Young children, particularly those aged four and younger, have the highest rate of TBI-related emergency room visits than any other age group. Psychiatric symptoms, including anxiety and mood disorders, have been...

Mild traumatic brain injuries (mTBIs), or concussions, account for 87% of all traumatic brain injuries (TBIs) in the United States and are a public health concern affecting an estimated 69 million people worldwide. MTBIs are often associated with cognitive impairments, such as attention deficits, but may also play a detrimental role in verbal language skills....

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. An estimated 20 to 55% of people with TBI will develop venous thromboembolism (VTE), a condition that includes the formation of blood clots in the leg (called deep vein thrombosis; DVT) and the dislodging and travel of one or more of these...

Neuroscientists have long understood that damage to specific areas of the brain can produce specific neuropsychiatric outcomes. Studies have shown that damage to the cortico-striato-thalamo-cortical (CSTC) circuit, a neural pathway between several important brain regions that regulate movement and other key functions, can cause abnormal repetitive behaviors in both animals and humans. These can include...

Mental disorders are one of the most common outcomes of traumatic brain injury (TBI). About 1 in 3 individuals who sustain a TBI will develop depression in the following six months, and about half will develop depression within a year. Furthermore, half of those with post-injury depression will also experience generalized anxiety. Ample research has...

The symptoms associated with mild traumatic brain injury (mTBI), also called concussion, typically resolve within a few weeks. One of the most common symptoms is noise sensitivity, which can cause discomfort and distress in loud, crowded environments, or even in response to small sounds that non-injured people barely perceive. While the vast majority of individuals...